Kinetoplast Division Factors in a Trypanosome
نویسندگان
چکیده
منابع مشابه
Division and DNA synthesis in the kinetoplast ofCrithidia fasciculata.
In Critliidia fascicuJata division of the kinetoplast occurs prior to karyokinesis. Kinetoplast division involves the lateral replication of the nucleoid, and the subsequent constriction and 'pinching off' of the nucleoid and mitochondrial components. Two subunits are produced. DNA synthesis in the kinetoplast and the nucleus is overlapping but asynchronous. Experiments for short labelling time...
متن کاملPNT1 Is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast*
The structure of a C11 peptidase PmC11 from the gut bacterium, Parabacteroides merdae, has recently been determined, enabling the identification and characterization of a C11 orthologue, PNT1, in the parasitic protozoon Trypanosoma brucei. A phylogenetic analysis identified PmC11 orthologues in bacteria, archaea, Chromerids, Coccidia, and Kinetoplastida, the latter being the most divergent. A p...
متن کاملMolecular dynamics studies of sequence-directed curvature in bending locus of trypanosome kinetoplast DNA.
The macroscopic curvature induced in the double helical B-DNA by regularly repeated adenine tracts (A-tracts) plays an exceptional role in structural studies of DNA because this effect presents the most well documented example of sequence specific conformational modulations. Recently, a new hypothesis of its physical origin has been put forward. According to it, the intrinsic bends in B-DNA may...
متن کاملFactors Affecting Trypanosome Maturation in Tsetse Flies
Trypanosoma brucei brucei infections which establish successfully in the tsetse fly midgut may subsequently mature into mammalian infective trypanosomes in the salivary glands. This maturation is not automatic and the control of these events is complex. Utilising direct in vivo feeding experiments, we report maturation of T. b. brucei infections in tsetse is regulated by antioxidants as well as...
متن کاملMultiplication of Trypanosoma pacifica (Euglenozoa: Kinetoplastea) in English sole, Parophrys vetulus, from Oregon coastal waters.
Multiplication of Trypanosoma pacifica was common in the fish host from observations of live flagellates and Giemsa-stained blood smears. Multiplication began with the elongation of the kinetoplast, thickening of the posterior portion of the body, and appearance of a new flagellum near the kinetoplast. The new flagellum was very rigid when less than 3 microm in length, but it became flexible as...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Trends in Parasitology
سال: 2019
ISSN: 1471-4922
DOI: 10.1016/j.pt.2018.11.002